|Scientific Subdivisions | The Journal of Molecular Diagnostics
Contact AMP | Sign In | Join / Renew | Go To CHAMP
This project is focused on the development of a guideline that addresses the requirements for the analytical validation of NGS as it pertains to the detection of somatic variants.Â Project is chaired by Dr. Larry Jennings (Lurie Children’s Hospital).
This project is focused on the development of recommendations for standards in interpretation of somatically acquired sequence variations building upon previous work in inherited conditions developed by an ACMG-AMP-CAP coalition. Project is chaired by Dr. Marilyn Li (Childrens Hospital of Philadelphia).
Led by Drs. Bert Gold and Milena Cankovic. Manuscript published in JMD in May 2015
The MSI working group met in November 2004 and discussed aspects of microsatellite instability (MSI) testing in colon cancer. The group is currently assembling a manuscript to address a number of areas of potential concern that laboratories may have in the implementation of MSI testing, including what tissue to test, which loci to examine, how to integrate immunohistochemistry, test interpretation and reporting and pitfalls. Project led by Dr. Deborah Dillon.
More information about the activities of the Clinical Practice Committee can be found in the Committee Report section of each AMP Newsletter.