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OGM shows promise for multiple myeloma
April 14, 2025
OGM shows promise for multiple myeloma

A study published in The Journal of Molecular Diagnostics integrated optical genome mapping approach to establish "the cytogenomic profile of the tumor on a scale suitable for routine practice in cytogenetics laboratories."

 

Digital PCR can reliably determine If CML patients in remission can discontinue treatment
March 27, 2025
Digital PCR can reliably determine If CML patients in remission can discontinue treatment

A study published in The Journal of Molecular Diagnostics shows that BCR::ABL1 digital PCR is more sensitive and accurate than conventional real-time quantitative PCR, making it a valuable tool to identify whether patients in deep molecular remission can successfully discontinue their chronic drug treatment.

New technique to measure circulating tumor DNA in metastatic cancer
February 25, 2025
New technique to measure circulating tumor DNA in metastatic cancer

A study published in The Journal of Molecular Diagnostics highlights the importance of monitoring tumor-specific mutations and introduces a dual threshold classifier to interpret circulating tumor DNA levels.

Gene variant common in individuals of African ancestry may lead to reduced metabolism of the thiopurine class of drugs
December 10, 2024
Gene variant common in individuals of African ancestry may lead to reduced metabolism of the thiopurine class of drugs

A study published in The Journal of Molecular Diagnostics emphasizes the need to understand the function of TPMT∗8 to ensure testing to predict thiopurine tolerance is effective, regardless of ancestry.

Simple test for flu could improve diagnosis and surveillance
June 21, 2024
Simple test for flu could improve diagnosis and surveillance

A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus. The work was reported in The Journal of Molecular Diagnostics.

Detecting pathogens faster and more accurately by melting DNA
February 21, 2024
Detecting pathogens faster and more accurately by melting DNA

A new analysis method, reported in The Journal of Molecular Diagnostics, can detect pathogens in blood samples faster and more accurately than blood cultures. It is also less likely to generate false positives compared to other emerging DNA detection-based technologies, such as next generation sequencing. 

Tell Congress: Prioritize patients over gene patents
August 14, 2023
Tell Congress: Prioritize patients over gene patents

On July 27, 2023, molecular professionals from around the United States met with the offices of their elected representatives to express opposition to the Patent Eligibility Restoration Act of 2023. This concerning legislation would reverse a unanimous 2013 Supreme Court decision that has led to a decade of unprecedented scientific innovations and aided the U.S. testing response to the COVID-19 pandemic.

The COVID-19 testing conundrum: What consumers should know about the different types of tests
August 18, 2021
The COVID-19 testing conundrum: What consumers should know about the different types of tests

Samuel Caughron and Timothy J. O'Leary, members of the AMP COVID Response Steering Committee, explore different types of tests available to consumers as the fall flu season approaches.

In-system clinical laboratories kept our hospitals open and solvent during COVID-19
June 15, 2021
In-system clinical laboratories kept our hospitals open and solvent during COVID-19

Karen L. Kaul, MD, PhD, a member of the AMP COVID Response Steering Committee, provides an assessment on how in-system labs were instrumental in keeping institutions functioning and solvent during the pandemic.

Critical COVID-19 testing factors local businesses should consider to help accelerate a safe reopening
May 26, 2021
Critical COVID-19 testing factors local businesses should consider to help accelerate a safe reopening

Donna M. Wolk, PhD, Chair of the AMP Infectious Diseases Subdivision, shares a quick checklist for organizations looking to contract a clinical laboratory for COVID-19 screening testing as part of its reopening strategy.

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