Testing Resources for Mpox

AMP has assembled a list of available resources on testing for Mpox.  This page will change as new information becomes available.  Please check back frequently for updates.

AMP

• AMP Alert: Update on FDA Deadlines for Mpox Test Notification and EUA Intent to Apply
• AMP update from Sept 8, 2022   
• Mpox Positive Control Resources:
  • Twist Bioscience
  • NIST MPXV (Mpox) Synthetic DNA PCR Standards
  • ATCC Quantitative Synthetic Mpox virus DNA 
  • Local public Health Laboratories

  • BEI Resources

    • NR-4928   Genomic DNA from Mpox Virus, USA-2003
    • NR-2500  Mpox Virus, USA-2003

Mpox Outbreak Maps

• CDC
• European Centre for Disease Prevention and Control (ECDC)
• Global Health
• Our World In Data
• Reuters
• WHO

AMA

• Orthopoxvirus and mpox coding & guidance

APHL

• Mpox Response Page
• Mpox Biosafety Fact Sheet
• APHL Member Laboratories

Association for Professionals in Infection Control and Epidemiology (APIC)

• Mpox in the United States: What You Need to Know

ASM

• Mpox Resources Page

ASPR

• NEW DECLARATION THAT CIRCUMSTANCES EXIST JUSTIFYING AUTHORIZATIONS PURSUANT TO SECTION 564 OF THE FEDERAL FOOD, DRUG, AND COSMETIC ACT, 21 U.S.C. § 360bbb-3(b)

CDC

• Tips For Adequate Collection of a Lesion Specimen From a Suspect Mpox Virus Case
• Case Definitions for Use in the 2022 Mpox Response
• Preparation and Collection of Specimens
• Diagnostic Process for Mpox virus Testing for Non-LRN Laboratories 
• Occupational Exposure to Orthopoxviruses Among Laboratory Personnel
• Health Alert Network (HAN)
  • Severe Manifestations of Mpox among People who are Immunocompromised Due to HIV or Other Conditions
  • Update for Clinicians on Mpox in People with HIV, Children and Adolescents, and People who are Pregnant or Breastfeeding
• Morbidity and Mortality Weekly Report (MMWR)
  • Mpox in a Young Infant — Florida, 2022
  • High-Contact Object and Surface Contamination in a Household of Persons with Mpox Virus Infection — Utah, June 2022
  •  Epidemiologic and Clinical Characteristics of Mpox Cases — United States, May 17–July 22, 2022
  • Interim Guidance for Prevention and Treatment of Mpox in Persons with HIV Infection — United States, August 2022
  • Rapid Diagnostic Testing for Response to the Mpox Outbreak — Laboratory Response Network, United States, May 17–June 30, 2022
  • Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022 NOTE: erratum published 
  • Mpox Outbreak — Nine States, May 2022
  • Orthopoxvirus Testing Challenges for Persons in Populations at Low Risk or Without Known Epidemiologic Link to Mpox — United States, 2022
  • Two Cases of Mpox-Associated Encephalomyelitis — Colorado and the District of Columbia, July–August 2022
  • Health Care Personnel Exposures to Subsequently Laboratory-Confirmed Mpox Patients — Colorado, 2022
• 2022 U.S. Mpox Outbreak – Situation Summary
• Mpox Information For Laboratory Personnel
• Laboratory Process for Mpox Virus Testing
• Laboratory Procedures and Biosafety Guidelines
• How to Report Results from Orthopoxvirus, Non-Variola Orthopoxvirus, and Mpox Virus Laboratory Diagnostic Testing
•     Real-Time PCR Assays
  • Non-variola Orthopoxvirus Generic Real-Time PCR Test Procedure
  • Mpox Generic PCR Protocol
  • Real-time PCR assays for the specific detection of mpox virus West African and Congo Basin strain DNA
  • Detection of mpox virus with real-time PCR assays

FDA

• List of Laboratories Offering Notified Laboratory-Developed Monkeypox Tests
• Policy for Mpox Tests to Address the Public Health Emergency
• Mpox Emergency Use Authorizations for Medical Devices
• Mpox Response

United Kingdom Health Security Agency (UK HSA)

• Mpox: diagnostic testing
• Mpox in the United States: What You Need to Know

European Society of Clinical Microbiology and Infectious Diseases

• ESCMID/IDSA joint web symposium on Monkeypox WEBINAR (free to access)
• www.escmid.org

Public Health Agency of Canada (PHAC)

• Mpox: Outbreak update

IDSA

• Mpox Resources Page

WHO

• Mpox
• Laboratory testing for the Mpox virus: Interim guidance

Other Resources

Center for Infectious Disease Research and Policy (CIDRAP), Univ of Minnesota

European Centre for Disease Prevention and Control (ECDC)

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