Testing Resources for Mpox

AMP has assembled a list of available resources on testing for Mpox.  This page will change as new information becomes available.  Please check back frequently for updates.

As a reminder for AMP Members, feel free to use the CHAMP community when you have questions for your AMP colleagues regarding Mpox.

AMP

• AMP Alert: Update on FDA Deadlines for Mpox Test Notification and EUA Intent to Apply
• AMP update from Sept 8, 2022   
• Mpox Positive Control Resources:
  • Twist Bioscience
  • NIST MPXV (Mpox) Synthetic DNA PCR Standards
  • ATCC Quantitative Synthetic Mpox virus DNA 
  • Local public Health Laboratories

  • BEI Resources

    • NR-4928   Genomic DNA from Mpox Virus, USA-2003
    • NR-2500  Mpox Virus, USA-2003

Mpox Outbreak Maps

• CDC
• European Centre for Disease Prevention and Control (ECDC)
• Global Health
• Our World In Data
• Reuters
• WHO

AMA

• Orthopoxvirus and mpox coding & guidance

APHL

• Mpox Response Page
• Mpox Biosafety Fact Sheet
• APHL Member Laboratories

Association for Professionals in Infection Control and Epidemiology (APIC)

• Mpox in the United States: What You Need to Know

ASM

• Mpox Resources Page

ASPR

• NEW DECLARATION THAT CIRCUMSTANCES EXIST JUSTIFYING AUTHORIZATIONS PURSUANT TO SECTION 564 OF THE FEDERAL FOOD, DRUG, AND COSMETIC ACT, 21 U.S.C. § 360bbb-3(b)

CDC

• Tips For Adequate Collection of a Lesion Specimen From a Suspect Mpox Virus Case
• Case Definitions for Use in the 2022 Mpox Response
• Preparation and Collection of Specimens
• Diagnostic Process for Mpox virus Testing for Non-LRN Laboratories 
• Occupational Exposure to Orthopoxviruses Among Laboratory Personnel
• Health Alert Network (HAN)
  • Severe Manifestations of Mpox among People who are Immunocompromised Due to HIV or Other Conditions
  • Update for Clinicians on Mpox in People with HIV, Children and Adolescents, and People who are Pregnant or Breastfeeding
• Morbidity and Mortality Weekly Report (MMWR)
  • Mpox in a Young Infant — Florida, 2022
  • High-Contact Object and Surface Contamination in a Household of Persons with Mpox Virus Infection — Utah, June 2022
  •  Epidemiologic and Clinical Characteristics of Mpox Cases — United States, May 17–July 22, 2022
  • Interim Guidance for Prevention and Treatment of Mpox in Persons with HIV Infection — United States, August 2022
  • Rapid Diagnostic Testing for Response to the Mpox Outbreak — Laboratory Response Network, United States, May 17–June 30, 2022
  • Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022 NOTE: erratum published 
  • Mpox Outbreak — Nine States, May 2022
  • Orthopoxvirus Testing Challenges for Persons in Populations at Low Risk or Without Known Epidemiologic Link to Mpox — United States, 2022
  • Two Cases of Mpox-Associated Encephalomyelitis — Colorado and the District of Columbia, July–August 2022
  • Health Care Personnel Exposures to Subsequently Laboratory-Confirmed Mpox Patients — Colorado, 2022
• 2022 U.S. Mpox Outbreak – Situation Summary
• Mpox Information For Laboratory Personnel
• Laboratory Process for Mpox Virus Testing
• Laboratory Procedures and Biosafety Guidelines
• How to Report Results from Orthopoxvirus, Non-Variola Orthopoxvirus, and Mpox Virus Laboratory Diagnostic Testing
•     Real-Time PCR Assays
  • Non-variola Orthopoxvirus Generic Real-Time PCR Test Procedure
  • Mpox Generic PCR Protocol
  • Real-time PCR assays for the specific detection of mpox virus West African and Congo Basin strain DNA
  • Detection of mpox virus with real-time PCR assays

FDA

• List of Laboratories Offering Notified Laboratory-Developed Monkeypox Tests
• Policy for Mpox Tests to Address the Public Health Emergency
• Mpox Emergency Use Authorizations for Medical Devices
• Mpox Response

United Kingdom Health Security Agency (UK HSA)

• Mpox: diagnostic testing
• Mpox in the United States: What You Need to Know

European Society of Clinical Microbiology and Infectious Diseases

• ESCMID/IDSA joint web symposium on Monkeypox WEBINAR (free to access)
• www.escmid.org

Public Health Agency of Canada (PHAC)

• Mpox: Outbreak update

IDSA

• Mpox Resources Page

WHO

• Mpox
• Laboratory testing for the Mpox virus: Interim guidance

Other Resources

Center for Infectious Disease Research and Policy (CIDRAP), Univ of Minnesota

European Centre for Disease Prevention and Control (ECDC)

Disclaimer: With the exception of resources labeled above as having been generated by AMP,  links will take you to external websites. Resources above are the sole responsibility of the entity providing them. AMP does not endorse any commercial product or service. AMP makes no warranty, express or implied, regarding any commercial product or service, and hereby disclaims, the accuracy, completeness, timeliness or merchantability or fitness for a particular purpose of the content and associated materials presented above. AMP shall not be liable for any damages, including direct, indirect, special, incidental, or consequential or any other type of damages arising out of or related to the use of the information contained on this page or associated materials.